One extra sex chromosome

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Back to Health A to Z. Chromosomes are packages of genes found in every cell in the body. There are 2 types of chromosome, called the sex chromosomes, that determine the genetic sex of a baby.

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XYY syndrome is a rare chromosomal disorder that affects males. It is caused by the presence of an extra Y chromosome. Males normally have one X and one Y chromosome.

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In reality, an extra Y chromosome may go undetected and have no noticeable side-effects. Chromosomes are compact packages of DNA and proteins containing the genes that encode the genetic features of an organism. Humans have 23 pairs of chromosome, with one pair member donated by each parent.

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Klinefelter syndrome is a chromosomal condition in boys and men that can affect physical and intellectual development. Most commonly, affected individuals are taller than average are unable to father biological children infertile ; however the signs and symptoms of Klinefelter syndrome vary among boys and men with this condition. In some cases, the features of the condition are so mild that the condition is not diagnosed until puberty or adulthood, and researchers believe that up to 75 percent of affected men and boys are never diagnosed. Boys and men with Klinefelter syndrome typically have small testes that produce a reduced amount of testosterone primary testicular insufficiency.

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Most people have 46 chromosomes in each cell. In males, this typically includes one X chromosome and one Y chromosome XY. XYY syndrome is a genetic condition that occurs when a male has an extra copy of the Y chromosome in each of their cells XYY.

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The term Klinefelter syndrome KS describes a group of chromosomal disorder in which there is at least one extra X chromosome to a normal male karyotype, 46,XY. XXY aneuploidy is the most common disorder of sex chromosomes in humans, with prevalence of one in males. Other sex chromosomal aneuploidies have also been described, although they are much less frequent, with 48,XXYY and 48,XXXY being present in 1 per 17, to 1 per 50, male births.

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This page describes various types of chromosomal problems that can occur in newborn babies. Down syndrome trisomy 21trisomy 18, trisomy 13, and various other conditions are discussed. Chromosomal abnormalities are common causes of birth defects that can affect the brain and other parts of the body.

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Sex chromosome abnormalities may be caused by full or partial deletions or duplications of sex chromosomes. Chromosomes are structures within cells that contain DNA and many genes. A gene is a segment of deoxyribonucleic acid DNA and contains the code for a specific protein that functions in one or more types of cells in the body see Genes and Chromosomes for a discussion about genetics.

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Disorders of the sex chromosome like disorders of the autosomes can be either numerical or structural, and can be present in all cells or in a mosaic form. Clinical indications that should raise suspicions of a sex chromosome abnormality are:. These disorders are considered very common with incidence of about —

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Stronger focus on nutrition within health services could save 3. Humans are born with 46 chromosomes in 23 pairs. Most women are 46XX and most men are 46XY. Research suggests, however, that in a few births per thousand some individuals will be born with a single sex chromosome 45X or 45Y sex monosomies and some with three or more sex chromosomes 47XXX, 47XYY or 47XXY, etc.

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